Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Yao has been at the center of a hostile takeover battle for China's largest real estate developer China Vanke Co Ltd (000002.SZ).
《中国日报》(China Daily)援引中国旅游研究院(China Tourism Academy)和北京市旅游发展委员会(Beijing Commission of Tourism Development)的一篇报告称，污染状况加剧以及人民币升值，使得北京去年1月至11月间的外国游客数量从2012年同期的501万人下降至420万人。此前一份基于对国内旅行社的调查的报告显示，去年前三个季度赴北京旅游的游客数量较上年同期下降约50%。
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Colliding Neutron Stars
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
In 2011 the owner of the tomb was identified as Liu Fei (169BC-127BC) the first king of Jiangdu an autonomous kingdom within the Han Dynasty according to China News.
Trends and targets in antiviral phototherapy
Some 695 million netizens used mobile phones to access the Internet in 2016, with a growth rate exceeding 10 percent for the third straight year, the report said. Smartphone-based Internet use accounted for 95.1 percent of all Internet users, up from 90.1 percent in 2015.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
McDonald's (MCD, Fortune 500), the all-American fast food Mecca, announced it would put $20 billion towards share repurchases and dividends Thursday, jumping on board the buyback trend that has boomed over the past 18 months.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
'For now she wears a dab of lipstick and nail varnish.'
Pyongyang, which refers to Park as "human scum' has long condemned the balloon launches and in recen onths has stepped up its demands for Seoul to ban them.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
And, this year, Star Wars found its way onto the list as well, with ‘starwars’ claiming the 16th spot.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
The curbs are having an effect. Overall non-financial outbound investment fell 36 per cent in January from a year earlier to Rmb53bn ($7.8bn), the commerce ministry said on Thursday, following a 39 per cent drop in December.
The public prosecutor has decided to release several individuals and will proceed with the prosecution of at least five others.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Concerns about the vulnerability of some emerging economies and gyrations in financial markets over the past few days should not dent “cautious optimism” about the global economy this year, leading central bankers and officials said on Saturday.
Developer:Dontnod Entertainment, Square Enix
In the ranking of finance programmes for students already working in the industry, London Business School regains the top place it occupied between 2011 and 2015, while Judge Business School at Cambridge university drops back into second place.
Influenza neuraminidase: A druggable target for natural products
‘Jordan,’ ‘harley,’ ‘robert,’ ‘matthew,’ ‘daniel,’ ‘andrew,’ ‘andrea,’ and ‘joshua’ all made it on the list – along with ‘football,’ and ‘lakers.’
“Total new business increased at a modest pace that was little-changed from October. However, November data indicated that foreign demand continued to soften, with the latest expansion of new export business the slowest since June. ”
The World Cup, on the other hand, was searched for as both a sporting event and a cultural experience.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Social customer service kills the dreaded phone tree
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
"Quality supervision authorities at all levels must intensify quality supervision and keep cracking down on law violations to improve the quality of products and protect consumers' rights," said Mei Kebao, deputy head of the administration.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
As well as diversity, Mr Cook has championed sustainability and supply-chain transparency, including a commitment to reducing Apple’s use of conflict minerals. While hyper-efficient under Mr Cook’s management before he became chief executive, Apple’s supply chain has not always been something to boast about, with recurring complaints about working conditions.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The tightening drove some enterprises seek other financing options such as bonds or listing on the National Equities Exchange and Quotations (NEEQ).
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Release date: 2015
Inhibition of SARS coronavirus helicase by bismuth complexes
其实，在第一部iPhone手机发布的前一年，LG集团已经推出了全触屏手机。虽然那也不是第一台触屏手机。1992年，世界上第一台触屏手机IBM Simon发布。而触屏技术在"西蒙"之前已经出现。1965年，E·A·约翰逊发明了第一个触屏设备——平板电脑，截止到1995年，一直由空中交通管制员使用。本特·斯顿普和弗兰克·贝克(Frank Beck)在20世纪70年代早期发明了电容式触屏，与约翰逊所发明触屏不同的是，它不能用手指操作，而是需要使用触控笔。在1971年，山姆·赫斯特发明了第一台电阻式触屏，他称之为"电子图表"。手指和触控笔都可以对它进行操作。在1985年，惠普公司发明了世界上第一台触屏电脑H-P150。在1993年，苹果公司也发布了第一个触屏设备——牛顿个人电子助理设备。但此产品并不成功，它的销量很低。
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
2. The 2012 Ig Nobel Peace Prize
ESCP欧洲商学院(ESCP Europe)和美国麻省理工学院斯隆管理学院(MIT Sloan School of Management)也表现不错。两所学院的排名均上升5位，分别位居第三和第五。
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
The QUBE will remind you to recycle, monitor when the trash was last taken out, and tell you to change the air freshener. These are all things people usually remember to do anyway, by the smell and all, but now there's a $300 "elegant" stainless steel can that'll constantly remind you with annoying mobile alerts.
This is the second time that both enterprises and institutions have adjusted basic pension, since the first simultaneous adjustment in 2016.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
自2007年4月以来，全球最具价值品牌100强的品牌价值增长106%。同期标准普尔500指数(S&P 500)和MSCI明晟全球指数(MSCI world index)分别上涨61%和21%。
If you happen to be shy, sitting in the front row can be very uncomfortable at first, but I promise you, it's one of the best ways to pay attention to everything being taught. You can hear better. You can see everything on the board without having to crane your neck around the head in front of you.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
STEP 5: GET RID of most of your friends
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
But John Davies, head of institutional investment in the Hong Kong team at CBRE, the property services business, says that lower prices should make the market more reliable. “The market is showing characteristics of a mature market, which institutional investors understand better,” he says.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Estimates for the size of the industry vary but Goldman Sachs figures suggest that sector loans grew from Rmb6bn to Rmb83bn between 2012 and 2014.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Yunge from the Desert
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Charli XCX, 'Number 1 Angel'
But Mr Stevenson said “this might reflect that the US is being bolder than the EU in protecting domestic steel producers”.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Asli Erdogan, a novelist of the “dark, pessimistic,” is struggling to process her own grim experience: months in prison.
The first time an influenza virus was found to be transmitted directly from birds to people, with infections linked to exposure to poultry markets. Six people in Hong Kong died. This virus was different because it moved directly from chickens to people, rather than having been altered by infecting pigs as an intermediate host. In addition, many of the most severe illnesses occurred in young adults similar to illnesses caused by the 1918 Spanish flu virus.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
傲人的财务业绩和令人炫目的新科技，或许已足以让这位钢铁般坚定的苹果首席执行官赢得英国《金融时报》2014年年度人物(Person of the Year)的称号。但库克阐述自己价值观的勇气，同样让他与众不同。
"We will set the exact date and location for our operation in consideration of weather conditions, but it will not be publicised," said Park Sang-Hak, a former defector who has led a series of balloon launches
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
For the government, the job is to create a good environment and the necessary conditions for our people to use their own wisdom and hard work to generate golden opportunities for themselves, rather than just relying on the government to hand them a job.
4.Thank you so much! I just love it! – Because telling someone that their gift sucked would make me look like an insensitive jerk。
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
He's lately begun taking meetings with the likes of Marissa Mayer and Rupert Murdoch. (Murdoch is chairman of News Corp, which owns The Wall Street Journal.) Though D'Aloisio's net worth at this point is merely eye-popping, not obscene, in his own youthful way he seems every bit as formidable as relative gray-hairs like 27-year-old Tumblr founder David Karp or 29-year-old Facebook wunderkind Mark Zuckerberg. 'He captivates a room,' says Joshua Kushner, founder of Thrive Capital, an early backer of Summly. 'He is incredibly self-aware for his age.'
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
It was billed as the year in which female film-makers and women's issues would be in the spotlight. The festival opened with a film by a female director for the first time in 28 years, Isabella Rossellini chaired the Un Certain Regard jury and Salma Hayek convened a high-profile panel to discuss the role of women in cinema. There was plenty to talk about – but had anything really changed? The numbers seemed to speak for themselves: of the 19 films in competition, only two were directed by women. And then came 'Heelgate' – of which, more later… Faced with suggestions that the festival is sexist, artistic director Thierry Frémaux was having none of it. Cannes was being held to an unfairly high standard, he claimed, one not applied to other festivals like Venice or Berlin. His suggestion? Instead, people should “attack the Oscars”.
Joseph Keller、Raymond Goldstein、Patrick Warren和Robin Ball获此殊荣，他们的研究课题是“人类马尾辫中头发的运动及受力平衡”。
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
There is a natural human tendency to idealize and whitewash days of yore, to cast them in the rosy glow of the mind’s eye.
A modular microarray imaging system for highly specific COVID-19 antibody testing
In an industry enthralled to rehashed stories that strike a familiar chord with audiences, give Pixar credit for often trying something new and pushing their viewers into uncharted territories. Coco, directed by Toy Story 3’s Lee Unkrich, has a visual look based around Mexico’s Dia de los Muertos (Day of the Dead). It’s about a young boy named Miguel who idolises legendary guitar player Ernesto de la Cruz and wants to learn how to play as well as he could. So he goes on a transformative odyssey of self-discovery into the realm of the dead to find his long-deceased idol and learn some lessons about the nature of creativity and originality. Whether it can reach the heights of Pixar’s 2015 masterpiece Inside Out remains to be seen, but Coco should surely be a feast for the eyes. Released November 15 in France, November 22 in the US, Croatia and the Philippines, and November 30 in Israel. (Credit: Disney-Pixar)
There are no right or wrong answers, just be honest with yourself.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
You might think that our love of lists could be pinned on the Ten Commandments, but Umberto Eco says otherwise. “The list is the origin of the culture,” he once said on a subject he knows well, having written a book titled “The Infinity of Lists.” And culture wants “to make infinity comprehensible” and “to create order — not always, but often,” hence Homer’s catalogs in “The Iliad” and the roll call of never-completed household chores on my fridge. “We like lists because we don’t want to die,” Mr. Eco also said, which is the best explanation of the listicle that I’ve yet read.
At tech start-up conferences, such as Slush in Helsinki in December, everyone was talking about experiences. The coming year is likely to see a wider adoption of virtual reality, which places the user in a digitally enhanced environment, and augmented reality, which overlays digital information on to the real world, creating new digital businesses.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
John Williams's classic score still raises goosebumps over 40 years after this summer blockbuster hit theaters. Jaws preys on our primal fear of the unknown in deep waters, showing a small beach town ravaged by a series of attacks from a single killer shark. In recent years, environmentalists have stressed the generally nonthreatening nature of sharks, which kill an average of just eight swimmers each year.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
For the full year, profits rose 3.3 per cent, the slowest growth since at least 2008, when Chinese manufacturers were slammed by the global financial crisis.
Best Companies rank: 7
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Shanghai Pudong International Airport reported the lowest punctuality rate last year. Only 52.4% of flights took off on time, with delays averaging 48 minutes.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
The local court gave Zhou a lenient sentence due to the teenager's age and frank confession of the crime, according to the report.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
The drama was broadcast during the summer holiday, targeting young audiences who prefer fantasies and romances.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Next year, the mayor’s affordable housing plan, which calls for building or preserving 200,000 units of affordable housing over the next decade, will begin to take shape. It hinges on a policy that requires developers to build affordable housing in exchange for being allowed to construct taller and denser buildings in neighborhoods rezoned by the city. Developers and housing advocates alike are waiting to see what it will look like once the administration adds muscle and flesh to the bones of the proposal.
Anti-HIV drug repurposing against SARS-CoV-2
The company realised that "it was all a mistake and that he did it without thinking," a Google spokeswoman said last Wednesday.
While D'Aloisio spends 80 percent of his work time retooling and improving Summly (which has already been integrated into Yahoo!'s iPhone app), the other 20 percent is devoted to imagining the expansive challenges he'll take on next. He predicts there will be summarization programs that do for video what Summly does for the written word. He has grand thoughts about using technology to aid learning and would like to help fellow autodidacts while disrupting the old educational models.
As stars such as Kevin Spacey and Morgan Freeman were alleged to have assaulted or harassed performers, activists began using the hashtag to share their ordeals online.
Length-scale dependence of protein hydration-shell density
China produced an estimated 420.5 tonnes of gold last year, according to the World Gold Council. Over the same period, Chinese demand for gold rose by 4 per cent to 953.3 tonnes, it said.
The history of James Bond theme songs isn't quite as long as some might suspect, however. The first two films in the series – Dr. No and From Russia With Love – didn't have opening songs, they had orchestral arrangements. Dr. No even segued into a weird rendition of "Three Blind Mice." Later on, On Her Majesty's Secret Service gave the opening number amiss and snuck its theme song into the middle and end of the movie.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Rather than strangling the doctor (difficult, due to his injury) Jalava took the corny line as inspiration. He decided to go ahead and actually build a prosthetic finger that contains two gigabytes of digital storage. He can now jack his finger into a computer just by peeling back the nail to expose the USB plug. He can also remove the entire finger at any time and hand it to a friend to use.
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"The autonomous region has invested 4 billion yuan (around 600 million US dollars) to promote industries with local features in poor areas, and relocated 77,000 poor people last year," said Lu Huadong, deputy director with the office.