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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Yao has been at the center of a hostile takeover battle for China's largest real estate developer China Vanke Co Ltd (000002.SZ).
《中国日报》(China Daily)援引中国旅游研究院(China Tourism Academy)和北京市旅游发展委员会(Beijing Commission of Tourism Development)的一篇报告称,污染状况加剧以及人民币升值,使得北京去年1月至11月间的外国游客数量从2012年同期的501万人下降至420万人。此前一份基于对国内旅行社的调查的报告显示,去年前三个季度赴北京旅游的游客数量较上年同期下降约50%。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Colliding Neutron Stars
polish

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

《大汉情缘之云中歌》改编自桐华网络小说《云中歌》。它以西汉时期(公元前206年-公元220年)为背景,讲诉了名为云歌的女子、贵族公子孟珏和汉昭帝刘弗陵之间的传奇爱情。该剧和《琅琊榜》同月播出,风头却几乎被《琅琊榜》完全盖过。它也因历史漏洞广受诟病。对某些观众而言,杨颖的颜值恐怕是该剧吸引他们的唯一亮点。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

现在,Swyft一半的收入都来自于为格温o史蒂芬尼制作的这类广告。雷表示,Swyft每月收入的增长幅度在50% 到100%之间。另一半就来自销售贴纸——主要是靠知名运动队和《怪物史莱克》这样的娱乐品牌授权。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

In 2011 the owner of the tomb was identified as Liu Fei (169BC-127BC) the first king of Jiangdu an autonomous kingdom within the Han Dynasty according to China News.
格罗斯出尔反尔,不可理喻:四个月前他还警告说美联储正在构造一颗信贷超新星、一个新的信贷泡沫,这个泡沫将击垮贝南克资助华尔街庞氏骗局、吹起一个巨大金融泡沫、进而将美国之未来置于巨大风险之下的自负的、高风险的实验。
至少希拉里今年赢得了点什么。我相信她会非常兴奋。
美国总统vs韩美自由贸易协定

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Some 695 million netizens used mobile phones to access the Internet in 2016, with a growth rate exceeding 10 percent for the third straight year, the report said. Smartphone-based Internet use accounted for 95.1 percent of all Internet users, up from 90.1 percent in 2015.
创造一个学习空间,来帮助你最大限度地利用好学习时间。你是喜欢绝对的安静,抑或吵闹的音乐呢?你是喜欢在餐桌上办公,还是想关上门创造了一个安静的空间。理解你喜欢的类型,并创造属于自己的空间。
你的老板很差
从周日起,各地的观众都在叹息该剧剧终,至少从Twitter名人的帖子来看是这样的。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

vt. 抵押

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

McDonald's (MCD, Fortune 500), the all-American fast food Mecca, announced it would put $20 billion towards share repurchases and dividends Thursday, jumping on board the buyback trend that has boomed over the past 18 months.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

可穿戴设备公司Atlas Wearables创始人彼得o李表示,电池技术和用户的保守是可穿戴市场面临的两大障碍。他说,在一些情况下,电池技术需要有足够大的改进才能实现足以激发用户兴趣的体验,而在穿戴时间、充电时间、处理能力和产品特点上,各家公司也需要做出平衡。
2.《活力王子》中的王子几乎破产

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

美国电影学会选出了十部本年度最佳电影和电视剧。这些影片排名按字母表顺序排列,美国电影学院评审团选出这些影片的标准是促进了活动图像的艺术化、提升了美国艺术形式文化遗产的魅力、对观众和艺术者有所启发、在美国社会上占有一席之地。
《迈耶罗维茨的故事》由诺亚?鲍姆巴赫执导、网飞出品,影片不仅搞笑,而且是一部有潜力拿奖的作品。它让你在忍俊不禁的同时,会觉得这部电影真的太高明了。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 2月20日房地产板块资金流向一览
Open Access Review Article

Diagnostic technologies for COVID-19: a review

'For now she wears a dab of lipstick and nail varnish.'
Pyongyang, which refers to Park as "human scum' has long condemned the balloon launches and in recen onths has stepped up its demands for Seoul to ban them.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

该部门期望今年消费增长仍然能够强有力地带动经济增长。
worthwhile
来源:前十网
And, this year, Star Wars found its way onto the list as well, with ‘starwars’ claiming the 16th spot.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

这份报告还指出,中国现在共有594名以美元计的亿万富翁,这一数字超越了美国的535名,但是并没有一名中国富翁进入全球首富前20名。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 男子为争房产 和假儿子打官司
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The curbs are having an effect. Overall non-financial outbound investment fell 36 per cent in January from a year earlier to Rmb53bn ($7.8bn), the commerce ministry said on Thursday, following a 39 per cent drop in December.
The public prosecutor has decided to release several individuals and will proceed with the prosecution of at least five others.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

在最初的角色分配中,由迈克尔·基顿来扮演这个角色。不料,美国广播公司的高管们恳求编剧和制片人让杰克活下来,他们认为这个角色太讨人喜欢了,不应该这么快就被安排死去。编剧最终同意了。迈克尔·基顿并不想签约一部长篇电视剧,便由马修·福克斯代替他来扮演杰克的角色。接下来的电视剧情便众所周知了。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

“尽管我本质上是一名工程师和分析人员,但迄今为止我所做过的最重要的决定都与此无关,它们永远是基于直觉,”他去年在曾就读MBA的杜克大学(Duke University)对一名采访者表示。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 谁该为老旧房外立面维修埋单
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Concerns about the vulnerability of some emerging economies and gyrations in financial markets over the past few days should not dent “cautious optimism” about the global economy this year, leading central bankers and officials said on Saturday.
当地媒体上周三报道,中国西南部重庆市的一名学生因嫌同学上课吵闹而试图下毒,被判有期徒刑一年。
Developer:Dontnod Entertainment, Square Enix
In the ranking of finance programmes for students already working in the industry, London Business School regains the top place it occupied between 2011 and 2015, while Judge Business School at Cambridge university drops back into second place.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

‘Jordan,’ ‘harley,’ ‘robert,’ ‘matthew,’ ‘daniel,’ ‘andrew,’ ‘andrea,’ and ‘joshua’ all made it on the list – along with ‘football,’ and ‘lakers.’
“Total new business increased at a modest pace that was little-changed from October. However, November data indicated that foreign demand continued to soften, with the latest expansion of new export business the slowest since June. ”
The World Cup, on the other hand, was searched for as both a sporting event and a cultural experience.
彭博(Bloomberg)的调查分析此前预计1月份中国CPI应上升1.9%。
镜头切换到《爱乐之城》的演员和剧组人员那里,他们高兴得抱成一团了,但大家可以听到比蒂好像在说:“应该是爱玛?斯通。”而唐纳薇回应道:“什么?”当《爱乐之城》剧组上台领奖时,可以听到旁边的舞台管理人员说:“哦……哦!天啊!他拿错信封了!”

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

"某时,世界呈现给我们是相互分隔的,但是这些电影和电视作品让我们感觉世界是相通的,"美国电影学院的总裁兼首席执行官Bob Gazzale如是说。"美国电影学院奖表彰这些电影艺术家们,勇于挑战,让我们受到鼓舞,娱乐,又励志,最后让我们意识到,我们都有着同样的心跳,"
Social customer service kills the dreaded phone tree

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

9.Be Honest

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

"Quality supervision authorities at all levels must intensify quality supervision and keep cracking down on law violations to improve the quality of products and protect consumers' rights," said Mei Kebao, deputy head of the administration.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

As well as diversity, Mr Cook has championed sustainability and supply-chain transparency, including a commitment to reducing Apple’s use of conflict minerals. While hyper-efficient under Mr Cook’s management before he became chief executive, Apple’s supply chain has not always been something to boast about, with recurring complaints about working conditions.
adv.
2013年排名:12
据新华社报道,全国青少年校园足球办公室近日表示,2016年中国已经拥有13381所“足球专业学校”,而69个区县正在学校里试点足球项目。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

n. 路线,(固定)线路,途径
The tightening drove some enterprises seek other financing options such as bonds or listing on the National Equities Exchange and Quotations (NEEQ).
这个系列的特制镜框和太阳墨镜以“DVF|为谷歌眼镜设计”为标签,价格高达1,600美元以上。迄今为止,谷歌已经和雷朋(Ray-Ban)眼镜的生产商陆逊梯卡(Luxottica)以及其他几家提供时尚眼镜的公司如普拉达(Prada)等展开过合作。它还招募了曾在艺术网站Art.com担任首席市场官的时尚总监艾维o罗斯来领导谷歌眼镜团队。
9.在培养皿中跳动的心脏

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

['rep?twɑ:]
Release date: 2015

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

对于其他队伍而言,在球场上拥有良好判断力的德国也是一直非常出色的队伍。意大利也是世界杯上无法忽视的队伍,而拥有罗纳尔多的葡萄牙队将会是一直极具危险性的队伍。拥有众多的大将的比利时队也将成为人们口中津津乐道的黑马队伍。
韩国最大的整形医院之一,由权株创立的JK整形手术中心,近期开了一家旅馆来更好地服务顾客。这些顾客每次看病人均花费17675美元。
其实,在第一部iPhone手机发布的前一年,LG集团已经推出了全触屏手机。虽然那也不是第一台触屏手机。1992年,世界上第一台触屏手机IBM Simon发布。而触屏技术在"西蒙"之前已经出现。1965年,E·A·约翰逊发明了第一个触屏设备——平板电脑,截止到1995年,一直由空中交通管制员使用。本特·斯顿普和弗兰克·贝克(Frank Beck)在20世纪70年代早期发明了电容式触屏,与约翰逊所发明触屏不同的是,它不能用手指操作,而是需要使用触控笔。在1971年,山姆·赫斯特发明了第一台电阻式触屏,他称之为"电子图表"。手指和触控笔都可以对它进行操作。在1985年,惠普公司发明了世界上第一台触屏电脑H-P150。在1993年,苹果公司也发布了第一个触屏设备——牛顿个人电子助理设备。但此产品并不成功,它的销量很低。
['spekju.l?tiv]
这名法国女星将会和瑞恩·高斯林、迈克尔·法斯宾德、娜塔丽·波特曼共同出演新电影。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 呼和浩特处罚54家建材生产企业
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

4.统计学家
美国和欧洲钢铁行业指责中国受到高额补贴的钢铁部门向全球市场大量输出钢铁,以低于生产成本的价格“倾销”,拉低了国际价格。近年来钢铁价格暴跌已经造成从澳大利亚到英国、乃至美国部分工业中心的全球范围的工厂大量倒闭。
[m?'r?liti]

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 水泥漆和乳胶漆区别是啥?
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

2. The 2012 Ig Nobel Peace Prize
ESCP欧洲商学院(ESCP Europe)和美国麻省理工学院斯隆管理学院(MIT Sloan School of Management)也表现不错。两所学院的排名均上升5位,分别位居第三和第五。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The QUBE will remind you to recycle, monitor when the trash was last taken out, and tell you to change the air freshener. These are all things people usually remember to do anyway, by the smell and all, but now there's a $300 "elegant" stainless steel can that'll constantly remind you with annoying mobile alerts.
豆瓣网友“Weishenmeyaoxuefa”称:“这部剧中的武术场景很抢眼,演员们表演的是真功夫。”
This is the second time that both enterprises and institutions have adjusted basic pension, since the first simultaneous adjustment in 2016.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

单词eccentric 联想记忆:
自2007年4月以来,全球最具价值品牌100强的品牌价值增长106%。同期标准普尔500指数(S&P 500)和MSCI明晟全球指数(MSCI world index)分别上涨61%和21%。
If you happen to be shy, sitting in the front row can be very uncomfortable at first, but I promise you, it's one of the best ways to pay attention to everything being taught. You can hear better. You can see everything on the board without having to crane your neck around the head in front of you.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

STEP 5: GET RID of most of your friends

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 2017瓷砖渠道半年总结九条
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

But John Davies, head of institutional investment in the Hong Kong team at CBRE, the property services business, says that lower prices should make the market more reliable. “The market is showing characteristics of a mature market, which institutional investors understand better,” he says.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Estimates for the size of the industry vary but Goldman Sachs figures suggest that sector loans grew from Rmb6bn to Rmb83bn between 2012 and 2014.
安娜上班的地方位于富人区的一家购物中心的车库,她抱怨道:“我去上班的路上要多花费一小时,但我却得不到一个现场看球的机会。“

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

n. 综合症,典型表现
如果不是看作有利可图的投资的话,人们依然喜欢欣赏早期绘画大师的作品,从中获得愉悦。苏富比称,6000人参观了12月5日至9日的早期绘画大师作品拍卖会预展,而6月份的印象派和当代艺术品拍卖会的参观人数为6400人。很多历史悠久的画作的确在低端价位上找到了市场,在12月9日至10日的早期绘画大师作品日间拍卖会上,佳士得和苏富比的售出比例都很高,分别是67%和65%。
Yunge from the Desert
大型企业PMI为53.1,比上月下降0.7个百分点;中型企业PMI为49.8,回落1.3个百分点,意味着进入轻度收缩。小型企业PMI为49,下降0.4个百分点,意味着收缩加剧。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Charli XCX, 'Number 1 Angel'
But Mr Stevenson said “this might reflect that the US is being bolder than the EU in protecting domestic steel producers”.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Asli Erdogan, a novelist of the “dark, pessimistic,” is struggling to process her own grim experience: months in prison.
The first time an influenza virus was found to be transmitted directly from birds to people, with infections linked to exposure to poultry markets. Six people in Hong Kong died. This virus was different because it moved directly from chickens to people, rather than having been altered by infecting pigs as an intermediate host. In addition, many of the most severe illnesses occurred in young adults similar to illnesses caused by the 1918 Spanish flu virus.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

在电影《007:大破天幕杀机》中饰演邦女郎的贝纳尼丝·玛尔洛(Berenice Marlohe),已经确认加盟导演特伦斯·马立克(TerrenceMalick)执导的最新电影作品,目前此影片正在奥斯汀进行拍摄。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

5.品牌推广:增长了16.4%
傲人的财务业绩和令人炫目的新科技,或许已足以让这位钢铁般坚定的苹果首席执行官赢得英国《金融时报》2014年年度人物(Person of the Year)的称号。但库克阐述自己价值观的勇气,同样让他与众不同。
由于欧元危机的影响,希腊,意大利,葡萄牙以及西班牙的排名大幅下滑。然而下滑幅度最大的是由于近期的政治危机影响的埃及,缅甸,和沙特阿拉伯。
"We will set the exact date and location for our operation in consideration of weather conditions, but it will not be publicised," said Park Sang-Hak, a former defector who has led a series of balloon launches

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

For the government, the job is to create a good environment and the necessary conditions for our people to use their own wisdom and hard work to generate golden opportunities for themselves, rather than just relying on the government to hand them a job.
4.Thank you so much! I just love it! – Because telling someone that their gift sucked would make me look like an insensitive jerk。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

He's lately begun taking meetings with the likes of Marissa Mayer and Rupert Murdoch. (Murdoch is chairman of News Corp, which owns The Wall Street Journal.) Though D'Aloisio's net worth at this point is merely eye-popping, not obscene, in his own youthful way he seems every bit as formidable as relative gray-hairs like 27-year-old Tumblr founder David Karp or 29-year-old Facebook wunderkind Mark Zuckerberg. 'He captivates a room,' says Joshua Kushner, founder of Thrive Capital, an early backer of Summly. 'He is incredibly self-aware for his age.'
单词association 联想记忆:
排在榜单第三位的是31岁的克丽茜·泰根,她在过去的12个月里赚得1350万美金,首次跻身榜单。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Challenger说:“工作总会有的。公司总是在招聘,只是竞争更加残酷了。”
游泳、花样游泳、跳水、皮划艇、激流回旋、静水、赛艇、帆船、水球
湿疹的根本原因最终得到确认。科学家查到了一系列蛋白质和分子引起这种令人难以忍受的皮肤问题的途径,并指出丝聚合蛋白并非唯一的祸首,而我们过去却是这样认为的。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

It was billed as the year in which female film-makers and women's issues would be in the spotlight. The festival opened with a film by a female director for the first time in 28 years, Isabella Rossellini chaired the Un Certain Regard jury and Salma Hayek convened a high-profile panel to discuss the role of women in cinema. There was plenty to talk about – but had anything really changed? The numbers seemed to speak for themselves: of the 19 films in competition, only two were directed by women. And then came 'Heelgate' – of which, more later… Faced with suggestions that the festival is sexist, artistic director Thierry Frémaux was having none of it. Cannes was being held to an unfairly high standard, he claimed, one not applied to other festivals like Venice or Berlin. His suggestion? Instead, people should “attack the Oscars”.
Joseph Keller、Raymond Goldstein、Patrick Warren和Robin Ball获此殊荣,他们的研究课题是“人类马尾辫中头发的运动及受力平衡”。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

mask
在过去的一年中,20多个省推出鼓励学生创业的政策,在创业期间,允许学生休学2至8年,并保留其学籍。然而,很多行业内部坚持学生应该首先完成学业,并先工作几年。
There is a natural human tendency to idealize and whitewash days of yore, to cast them in the rosy glow of the mind’s eye.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 儿童家具安全隐患三大方面不达标
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

In an industry enthralled to rehashed stories that strike a familiar chord with audiences, give Pixar credit for often trying something new and pushing their viewers into uncharted territories. Coco, directed by Toy Story 3’s Lee Unkrich, has a visual look based around Mexico’s Dia de los Muertos (Day of the Dead). It’s about a young boy named Miguel who idolises legendary guitar player Ernesto de la Cruz and wants to learn how to play as well as he could. So he goes on a transformative odyssey of self-discovery into the realm of the dead to find his long-deceased idol and learn some lessons about the nature of creativity and originality. Whether it can reach the heights of Pixar’s 2015 masterpiece Inside Out remains to be seen, but Coco should surely be a feast for the eyes. Released November 15 in France, November 22 in the US, Croatia and the Philippines, and November 30 in Israel. (Credit: Disney-Pixar)
There are no right or wrong answers, just be honest with yourself.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

You might think that our love of lists could be pinned on the Ten Commandments, but Umberto Eco says otherwise. “The list is the origin of the culture,” he once said on a subject he knows well, having written a book titled “The Infinity of Lists.” And culture wants “to make infinity comprehensible” and “to create order — not always, but often,” hence Homer’s catalogs in “The Iliad” and the roll call of never-completed household chores on my fridge. “We like lists because we don’t want to die,” Mr. Eco also said, which is the best explanation of the listicle that I’ve yet read.
说到底,我预期这些新的领导人将开始从更广泛的候选人中选拔人员,并把不同背景的人任命为自己的直接下属,从而驳斥那些根据当前的失衡来外推还需数十年才能实现领导层男女平衡的悲观者。
At tech start-up conferences, such as Slush in Helsinki in December, everyone was talking about experiences. The coming year is likely to see a wider adoption of virtual reality, which places the user in a digitally enhanced environment, and augmented reality, which overlays digital information on to the real world, creating new digital businesses.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

债券大王比尔?格罗斯(Bill Gross)承认:“QE必须结束。”数万亿的低成本资金“扭曲了激励机制,将资产价格推高至人为水平”。但现在格罗斯说“美联储的计划可能过于仓促了”。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 家居品牌纷纷玩起跨界发展
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

6.杰克·谢帕德差点在第一集中死去
John Williams's classic score still raises goosebumps over 40 years after this summer blockbuster hit theaters. Jaws preys on our primal fear of the unknown in deep waters, showing a small beach town ravaged by a series of attacks from a single killer shark. In recent years, environmentalists have stressed the generally nonthreatening nature of sharks, which kill an average of just eight swimmers each year.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

foundation
单词accomplished 联想记忆:

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 建材行业如何化解品牌难题
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

For the full year, profits rose 3.3 per cent, the slowest growth since at least 2008, when Chinese manufacturers were slammed by the global financial crisis.
Best Companies rank: 7

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

根据中国国家统计局的数据,10月份中国规模以上工业增加值同比增长6.1%,与9月份的增幅一致,略低于经济学家的预期中值6.2%。
这个墓地在如今中国西北部的库车县被找到。已经有10个坟墓被挖掘出土,其中7个是大型的砖石结构。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 喜临门筹划重大事项 17日起停牌
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

n. 土耳其

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

斯卡曼德是个魔法生物研究学家。
卢彦说,通州和其他地区也会建设高规格的医院供市中心地区居民看病,该举措可以缓解交通压力和城市拥堵。
Shanghai Pudong International Airport reported the lowest punctuality rate last year. Only 52.4% of flights took off on time, with delays averaging 48 minutes.
10. 经济学在害死经济,但就像可卡因成瘾者一样,我们停不下来

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

商务部本月早些时候表示,消费品的零售销售是去年消费的一项关键指标。该销售额同比增长了10.7%,占去年全国66.4%的GDP增长。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 东莞家具展成了“捡漏王”
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

不过,行业、企业间的高管薪酬差距明显。
6.你昨天穿得比平时好看10倍。
The local court gave Zhou a lenient sentence due to the teenager's age and frank confession of the crime, according to the report.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The drama was broadcast during the summer holiday, targeting young audiences who prefer fantasies and romances.
澳大利亚管理研究生院的一名毕业生表示:“最初,我对攻读在线课程颇有疑虑,但沟通和在线互动非常棒。”

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

adj. 深思的,体贴的
经济增长率将会首次达到3%在这十年里

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Next year, the mayor’s affordable housing plan, which calls for building or preserving 200,000 units of affordable housing over the next decade, will begin to take shape. It hinges on a policy that requires developers to build affordable housing in exchange for being allowed to construct taller and denser buildings in neighborhoods rezoned by the city. Developers and housing advocates alike are waiting to see what it will look like once the administration adds muscle and flesh to the bones of the proposal.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The company realised that "it was all a mistake and that he did it without thinking," a Google spokeswoman said last Wednesday.
While D'Aloisio spends 80 percent of his work time retooling and improving Summly (which has already been integrated into Yahoo!'s iPhone app), the other 20 percent is devoted to imagining the expansive challenges he'll take on next. He predicts there will be summarization programs that do for video what Summly does for the written word. He has grand thoughts about using technology to aid learning and would like to help fellow autodidacts while disrupting the old educational models.
As stars such as Kevin Spacey and Morgan Freeman were alleged to have assaulted or harassed performers, activists began using the hashtag to share their ordeals online.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 家居上市企业中报8月密集披露
Paper

Length-scale dependence of protein hydration-shell density

[ik'si:d]
China produced an estimated 420.5 tonnes of gold last year, according to the World Gold Council. Over the same period, Chinese demand for gold rose by 4 per cent to 953.3 tonnes, it said.
stress
The history of James Bond theme songs isn't quite as long as some might suspect, however. The first two films in the series – Dr. No and From Russia With Love – didn't have opening songs, they had orchestral arrangements. Dr. No even segued into a weird rendition of "Three Blind Mice." Later on, On Her Majesty's Secret Service gave the opening number amiss and snuck its theme song into the middle and end of the movie.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

虽然总统那晚险胜,此次相逢与前两次辩论相比是诚恳且基本上平安无事的,不太可能对选举结果产生多大的影响。
谷歌英国的搜索结果分为热门趋势搜索榜和搜索次数排行榜。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Rather than strangling the doctor (difficult, due to his injury) Jalava took the corny line as inspiration. He decided to go ahead and actually build a prosthetic finger that contains two gigabytes of digital storage. He can now jack his finger into a computer just by peeling back the nail to expose the USB plug. He can also remove the entire finger at any time and hand it to a friend to use.
涨幅放慢也与房地产投资变化趋势吻合。上月,一二线城市的限购措施对房地产投资造成了(些许)冲击,全国范围内的房产成交量和成交金额的增速也有所减缓。
10.你真的很明显,好吧?

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 土地市场活跃 楼市出现分化
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[l?un]
"The autonomous region has invested 4 billion yuan (around 600 million US dollars) to promote industries with local features in poor areas, and relocated 77,000 poor people last year," said Lu Huadong, deputy director with the office.

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